학술논문
Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Natural killer (NK) cells are important immune cells for mediating antiviral immunity. Here the authors show that chronic hepatitis C virus infection in human can imprint lasting functional phenotypes in NK cells to increase their inter-individual but decrease intra-individual diversity.