학술논문

In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits
Document Type
article
Source
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Majority of human long non-coding RNAs (lncRNAs) are not conserved in mouse. Here the authors identify metabolic trait-associated lncRNA genes and show a functional role of a non-conserved human lncRNA, LINC01018, in lipid metabolism using a humanized mouse model.