학술논문

XANES spectroscopy for the clinician
Document Type
article
Source
Comptes Rendus. Chimie, Vol 25, Iss S1, Pp 189-208 (2021)
Subject
XANES
Medicine
Calcium
Platinum
Drug
Biochemistry
QD415-436
Physical and theoretical chemistry
QD450-801
Mathematics
QA1-939
Language
English
French
ISSN
1878-1543
Abstract
XANES spectroscopy, which uses synchrotron radiation as a probe, offers substantial information about the local structure of biological samples, encompassing those without long range order such as Pt anticancer molecules, and nanometre scale or amorphous particles of calcium phosphate. Its subcellular spatial resolution, as well as its capacity to operate at room temperatures and pressures represent major advantages for medical research. Moreover, paraffin embedded biopsy samples can be analysed without any further preparation, Key publications which illustrate these capacities are presented.