학술논문
Diagnostic significance of paradoxical left ventricular hypertrophy in detecting cardiac amyloidosis
Document Type
article
Author
Source
International Journal of Cardiology: Heart & Vasculature, Vol 49, Iss , Pp 101279- (2023)
Subject
Language
English
ISSN
2352-9067
Abstract
Background: Cardiac amyloidosis (CA) progresses rapidly with a poor prognosis. Therefore, methods for early diagnosis that are easily accessible in any hospital, are required. We hypothesized that based on the pathology of CA, morphological left ventricular hypertrophy (LVH) without electrical augmentation, namely paradoxical LVH, could be used to diagnose CA. This study aimed to investigate whether paradoxical LVH has diagnostic significance in identifying CA in patients with LVH. Methods: Patients who presented with left ventricular (LV) wall thickness ≥ 12 mm on cardiac magnetic resonance (CMR) were enrolled from a multicentre CMR registry. Paradoxical LVH was defined as a LV wall thickness ≥ 12 mm on CMR, SV1 + RV5