학술논문
Compared study of fucoidan from sea cucumber (Holothuria tubulosa) with different molecular weight on ameliorating β cell apoptosis
Document Type
article
Source
Journal of Functional Foods, Vol 83, Iss , Pp 104507- (2021)
Subject
Language
English
ISSN
1756-4646
Abstract
In this study, the effects of Holothuria tubulosa sea cucumber (Ht- FUC) with different molecular weight (Ht, Ht-1, Ht-2, Ht-3) on β cell apoptosis induced by high-fat-high-sucrose diet (HFD) in male C57BL/6J mice were investigated. After intervention with Ht-FUC (60 mg/kg body weight) for 16 weeks, results showed that different Ht-FUC could significantly decrease blood glucose and insulin levels, and reduce the burden of islet β cell secretion (P