학술논문
A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging
Document Type
article
Author
Liang Wang; Chunling Wu; Wanling Peng; Ziliang Zhou; Jianzhi Zeng; Xuelin Li; Yini Yang; Shuguang Yu; Ye Zou; Mian Huang; Chang Liu; Yefei Chen; Yi Li; Panpan Ti; Wenfeng Liu; Yufeng Gao; Wei Zheng; Haining Zhong; Shangbang Gao; Zhonghua Lu; Pei-Gen Ren; Ho Leung Ng; Jie He; Shoudeng Chen; Min Xu; Yulong Li; Jun Chu
Source
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
The second messenger cAMP modulates a wide range of important biological processes. Here, the authors developed a fluorescent indicator termed G-Flamp1, which can accurately report levels of cAMP in living cells.