학술논문
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy
Document Type
article
Author
Matt Lechner; Volker H. Schartinger; Christopher D. Steele; Wen Long Nei; Marc Lucas Ooft; Liesa-Marie Schreiber; Christodoulos P. Pipinikas; Grace Tin-Yun Chung; Yuk Yu Chan; Feng Wu; Ka-Fai To; Chi Man Tsang; Wayne Pearce; Daniele Morelli; Martin Philpott; Liam Masterson; Reshma Nibhani; Graham Wells; Christopher G. Bell; Julia Koller; Susanne Delecluse; Yim Ling Yip; Jacklyn Liu; Cillian T. Forde; Martin D. Forster; Amrita Jay; József Dudás; Annika Krapp; Simon Wan; Christian Uprimny; Susanne Sprung; Johannes Haybaeck; Tim R. Fenton; Kerry Chester; Christina Thirlwell; Gary Royle; Teresa Marafioti; Rajeev Gupta; Sagung Rai Indrasari; Camelia Herdini; Mohd Afiq Mohd Slim; I. Indrawati; Liam Sutton; Renske Fles; Bing Tan; Joe Yeong; Amit Jain; Shuting Han; Haitao Wang; Kelvin S. H. Loke; Wan He; Ruilian Xu; Hongtao Jin; Zhiqiang Cheng; David Howard; Peter H. Hwang; Quynh-Thu Le; Joshua K. Tay; Robert B. West; Sai Wah Tsao; Tim Meyer; Herbert Riechelmann; Udo Oppermann; Henri-Jacques Delecluse; Stefan M. Willems; Melvin L. K. Chua; Pierre Busson; Kwok Wai Lo; Guido Wollmann; Nischalan Pillay; Bart Vanhaesebroeck; Valerie J. Lund
Source
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Nasopharyngeal carcinoma (NPC) lacks effective diagnostic and therapeutic strategies, in particular at advanced stages. Here, the authors show that expression of the somatostatin receptor 2 is induced by Epstein-Barr virus in NPC and has a key role in the diagnosis, imaging, targeted therapies and prognosis of NPC.