학술논문

Characteristics and outcomes of women initiating ART during pregnancy versus breastfeeding in Option B+ in Malawi
Document Type
article
Source
BMC Public Health, Vol 16, Iss 1, Pp 1-7 (2016)
Subject
Option B+
Prevention of mother to child transmission of HIV
ART initiation
Malawi
Pregnancy
Breastfeeding
Public aspects of medicine
RA1-1270
Language
English
ISSN
1471-2458
Abstract
Abstract Background Malawi adopted the PMTCT strategy ‘Option B+’ in 2011, providing life-long ART for all HIV-infected pregnant and breastfeeding women. We explored differences in characteristics and outcomes of women initiating ART during pregnancy versus breastfeeding. Methods We conducted a retrospective cohort analysis of women in Zomba District, southern Malawi, from January 2012- September 2013. Data were extracted from the Zomba District Observational Cohort Study, a surveillance project collecting data from standardized Ministry of Health ART monitoring tools. Results 1986 (67.2 %) women initiated ART during pregnancy and 969 (32.8 %) during breastfeeding. Women initiating ART in breastfeeding were more likely to be > 30 years (aOR = 1.33, 95 % CI1.11–1.59, p = 0.003) and have WHO Stage 3/4 (aOR = 2.74, 95 % CI1.94–3.87, p