학술논문
Clinical Features and Outcomes of Patients With Malignancy and Takotsubo Syndrome: Observations From the International Takotsubo Registry
Document Type
article
Author
Victoria L. Cammann; Annahita Sarcon; Katharina J. Ding; Burkhardt Seifert; Ken Kato; Davide Di Vece; Konrad A. Szawan; Sebastiano Gili; Stjepan Jurisic; Beatrice Bacchi; Jozef Micek; Antonio H. Frangieh; L. Christian Napp; Milosz Jaguszewski; Eduardo Bossone; Rodolfo Citro; Fabrizio D'Ascenzo; Jennifer Franke; Michel Noutsias; Maike Knorr; Susanne Heiner; Christof Burgdorf; Wolfgang Koenig; Holger Thiele; Carsten Tschöpe; Lawrence Rajan; Guido Michels; Roman Pfister; Alessandro Cuneo; Claudius Jacobshagen; Mahir Karakas; Adrian Banning; Florim Cuculi; Richard Kobza; Thomas A. Fischer; Tuija Vasankari; K. E. Juhani Airaksinen; Rafal Dworakowski; Christoph Kaiser; Stefan Osswald; Leonarda Galiuto; Wolfgang Dichtl; Clément Delmas; Olivier Lairez; John D. Horowitz; Martin Kozel; Petr Widimský; Petr Tousek; David E. Winchester; Ekaterina Gilyarova; Alexandra Shilova; Mikhail Gilyarov; Ibrahim El‐Battrawy; Ibrahim Akin; Christian Ukena; Johann Bauersachs; Burkert M. Pieske; Gerd Hasenfuß; Wolfgang Rottbauer; Ruediger C. Braun‐Dullaeus; Grzegorz Opolski; Philip MacCarthy; Stephan B. Felix; Martin Borggrefe; Carlo Di Mario; Filippo Crea; Hugo A. Katus; Heribert Schunkert; Thomas Münzel; Michael Böhm; Jeroen J. Bax; Abhiram Prasad; Jerold Shinbane; Thomas F. Lüscher; Frank Ruschitzka; Jelena R. Ghadri; Christian Templin
Source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 15 (2019)
Subject
Language
English
ISSN
2047-9980
Abstract
Background Clinical characteristics and outcomes of takotsubo syndrome (TTS) patients with malignancy have not been fully elucidated. This study sought to explore differences in clinical characteristics and to investigate short‐ and long‐term outcomes in TTS patients with or without malignancy. Methods and Results TTS patients were enrolled from the International Takotsubo Registry. The TTS cohort was divided into patients with and without malignancy to investigate differences in clinical characteristics and to assess short‐ and long‐term mortality. A subanalysis was performed comparing long‐term mortality between a subset of TTS patients with or without malignancy and acute coronary syndrome (ACS) patients with or without malignancy. Malignancy was observed in 16.6% of 1604 TTS patients. Patients with malignancy were older and more likely to have physical triggers, but less likely to have emotional triggers compared with those without malignancy. Long‐term mortality was higher in patients with malignancy (P