학술논문

Body Temperature Measurements for Metabolic Phenotyping in Mice
Document Type
article
Source
Frontiers in Physiology, Vol 8 (2017)
Subject
mouse
phenotyping
body temperature
thermography
metabolism
telemetric recordings
Physiology
QP1-981
Language
English
ISSN
1664-042X
Abstract
Endothermic organisms rely on tightly balanced energy budgets to maintain a regulated body temperature and body mass. Metabolic phenotyping of mice, therefore, often includes the recording of body temperature. Thermometry in mice is conducted at various sites, using various devices and measurement practices, ranging from single-time probing to continuous temperature imaging. Whilst there is broad agreement that body temperature data is of value, procedural considerations of body temperature measurements in the context of metabolic phenotyping are missing. Here, we provide an overview of the various methods currently available for gathering body temperature data from mice. We explore the scope and limitations of thermometry in mice, with the hope of assisting researchers in the selection of appropriate approaches, and conditions, for comprehensive mouse phenotypic analyses.