학술논문
Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project
Document Type
article
Author
Matteo Bassetti; Daniele R. Giacobbe; Antonio Vena; Cecilia Trucchi; Filippo Ansaldi; Massimo Antonelli; Vaclava Adamkova; Cristiano Alicino; Maria-Panagiota Almyroudi; Enora Atchade; Anna M. Azzini; Novella Carannante; Alessia Carnelutti; Silvia Corcione; Andrea Cortegiani; George Dimopoulos; Simon Dubler; José L. García-Garmendia; Massimo Girardis; Oliver A. Cornely; Stefano Ianniruberto; Bart Jan Kullberg; Katrien Lagrou; Clement Le Bihan; Roberto Luzzati; Manu L. N. G. Malbrain; Maria Merelli; Ana J. Marques; Ignacio Martin-Loeches; Alessio Mesini; José-Artur Paiva; Maddalena Peghin; Santi Maurizio Raineri; Riina Rautemaa-Richardson; Jeroen Schouten; Pierluigi Brugnaro; Herbert Spapen; Polychronis Tasioudis; Jean-François Timsit; Valentino Tisa; Mario Tumbarello; Charlotte H. S. B. van den Berg; Benoit Veber; Mario Venditti; Guillaume Voiriot; Joost Wauters; Philippe Montravers
Source
Critical Care, Vol 23, Iss 1, Pp 1-7 (2019)
Subject
Language
English
ISSN
1364-8535
Abstract
Abstract Background The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. Methods A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal candidiasis in European ICU project (EUCANDICU). Results During the study period, 570 episodes of ICU-acquired IC were observed, with a cumulative incidence of 7.07 episodes per 1000 ICU admissions, with important between-center variability. Separated, non-mutually exclusive cumulative incidences of candidemia and IAC were 5.52 and 1.84 episodes per 1000 ICU admissions, respectively. Crude 30-day mortality was 42%. Age (odds ratio [OR] 1.04 per year, 95% CI 1.02–1.06, p