학술논문

Are de novo acute heart failure and acutely worsened chronic heart failure two subgroups of the same syndrome?
Document Type
article
Source
Srpski Arhiv za Celokupno Lekarstvo, Vol 138, Iss 3-4, Pp 162-169 (2010)
Subject
acute heart failure
echocardiography
natriuretic Peptides
Medicine
Language
English
Serbian
ISSN
0370-8179
Abstract
Introduction. Acute heart failure (AHF) is one of the most common diseases in emergency medicine, associated with poor prognosis and high in-hospital and long-term mortality. Objective. To investigate clinical presentation of patients with de novo AHF and acute worsening of chronic heart failure (CHF) and to identify differences in blood levels of biomarkers and echocardiography findings. Methods. This prospective study comprised 64 consecutive patients being grouped according to the onset of the disease into patients with the de novo AHF (45.3%), and patients with acute worsening of CHF (54.7%). Results. Acute congestion (60%) was the most common manifestation of de novo AHF, whereas pulmonary oedema (43.1%) was the most common manifestation of acutely decompensated CHF. Patients with acutely decompensated CHF had significantly higher blood values of creatinine (147.10 vs 113.16 μmol/l; p