학술논문
Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
Three X-ray structures are presented of human aldehyde dehydrogenase family 1 member A3 (ALDH1A3), a potential cancer stem cell biomarker (alone, with NAD+ and with ATP) and structure determination performed using molecular replacement.