학술논문
Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium
Document Type
article
Author
Source
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Through regeneration, the endometrium accumulates somatic mutations that can lead to diseases like endometriosis and cancer. Here, the authors use genomics to analyse normal endometrial glands from different patient cohorts, detect rhizome structures with common clonal ancestors and infer clonal expansion dynamics.