학술논문
COVID-19 in an immunocompromised host: persistent shedding of viable SARS-CoV-2 and emergence of multiple mutations: a case report
Document Type
article
Author
Source
International Journal of Infectious Diseases, Vol 114, Iss , Pp 178-182 (2022)
Subject
Language
English
ISSN
1201-9712
Abstract
ABSTRACT: This article reports a case of a 21-year-old woman with refractory B-cell acute lymphocytic leukaemia who presented with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). She remained positive for SARS-CoV-2 by viral culture for 78 days and by polymerase chain reaction (PCR) for 97 days. Sequencing of repeat samples over time demonstrated an increasing and dynamic repertoire of mutations.