학술논문
Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
Document Type
article
Source
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
mTORC1 is a critical kinase that regulates cell growth and proliferation. Here the authors show that glutamine metabolism is sufficient to restore mTORC1 activity during prolonged amino acid starvation in an autophagy-dependent manner.