학술논문
International experience by using of the SJMB protocols in treatment of children with medulloblastoma in the age group over 3 years (literature review)
Document Type
article
Author
Source
Современная онкология, Vol 25, Iss 3, Pp 385-390 (2023)
Subject
Language
Russian
ISSN
1815-1434
1815-1442
18151434
1815-1442
18151434
Abstract
During the last 30 years, unique international experience has been accumulated in the treatment of children with medulloblastoma, especially in the age group over 3 years. Evolutionary representations about one of the most well – known international protocols – SJMB (in versions since 1996 – SJMB96, since 2003 – SJMB03, since 2012 – SJMB12) are shown in this article. Innovative criteria for stratifying patients into risk groups were established according to clinical, therapeutic, morphological and molecular-biological prognostic factors. Despite the accumulated experience, it is necessary to continue studying the relationship between age groups and the molecular biology of tumor cells for the purpose of subsequent optimization of the treatment program.