학술논문
Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
Document Type
article
Author
Khadija Khan; Farina Karim; Yashica Ganga; Mallory Bernstein; Zesuliwe Jule; Kajal Reedoy; Sandile Cele; Gila Lustig; Daniel Amoako; Nicole Wolter; Natasha Samsunder; Aida Sivro; James Emmanuel San; Jennifer Giandhari; Houriiyah Tegally; Sureshnee Pillay; Yeshnee Naidoo; Matilda Mazibuko; Yoliswa Miya; Nokuthula Ngcobo; Nithendra Manickchund; Nombulelo Magula; Quarraisha Abdool Karim; Anne von Gottberg; Salim S. Abdool Karim; Willem Hanekom; Bernadett I. Gosnell; COMMIT-KZN Team; Richard J. Lessells; Tulio de Oliveira; Mahomed-Yunus S. Moosa; Alex Sigal
Source
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Emerging SARS-CoV-2 Omicron sub-lineages BA.4 and BA.5 raise concerns about potential immune evasion. Here, Khan et al. show that both BA.4 and BA.5 are able to escape immune response induced by prior BA.1 infection, but that this effect is less pronounced in vaccinated individuals.