학술논문
Relationship between arterial stiffness, left ventricular diastolic function, and renal function in chronic kidney disease
Document Type
article
Source
BMC Nephrology, Vol 24, Iss 1, Pp 1-13 (2023)
Subject
Language
English
ISSN
1471-2369
Abstract
Abstract Aim In chronic kidney disease, IgA nephropathy, and left ventricular diastolic dysfunction have prognostic significance as well. However, the relationship between diastolic dysfunction, arterial stiffness, and renal function has not been fully elucidated. Methods 79 IgA nephropathy patients (aged 46 ± 11 years) and 50 controls were investigated. Tissue Doppler imaging was used to measure early (Ea) and late (Aa) diastolic velocities. Arterial stiffness was measured by a photoplethysmographic (stiffness index (SI)) and an oscillometric method (aortic pulse wave velocity (PWVao)). Results We compared the IgAN patients to a similar cardiovascular risk group with a preserved eGFR. A strong correlation was found between Ea/Aa and SI (p