학술논문

Severity of SARS-CoV-2 Omicron XBB subvariants in Singapore
Document Type
article
Source
The Lancet Regional Health. Western Pacific, Vol 37, Iss , Pp 100849- (2023)
Subject
Public aspects of medicine
RA1-1270
Language
English
ISSN
2666-6065
Abstract
Summary: Several XBB subvariants such as XBB.1.5, XBB.1.9, XBB.1.16 and XBB.2.3 co-circulate in Singapore. Despite the different viral properties of XBB.1.16 as compared to other XBB subvariants, comparison on their severity is limited. In this study, we investigate the outcomes of hospitalisation and severe COVID-19 infection in individuals infected with different XBB subvariants, adjusted for potential confounders such as age and vaccination history. Overall, our preliminary analysis showed that the risk of severe outcomes when infected with XBB.1.16 is higher than that of XBB.1.5 or XBB.1.9 but there is no difference in the risk of hospitalisation across different XBB subvariants.