학술논문
Retrospective analysis of the incidence and outcome of late acute and chronic graft-versus-host disease—an analysis from transplant centers across Europe
Document Type
article
Author
Ronja Langer; Antonela Lelas; Michael Rittenschober; Agnieszka Piekarska; Alicja Sadowska-Klasa; Ivan Sabol; Lana Desnica; Hildegard Greinix; Anne Dickinson; Marit Inngjerdingen; Anita Lawitschka; Radovan Vrhovac; Drazen Pulanic; Sibel Güneş; Stefan Klein; Jan Moritz Middeke; Matthias Grube; Matthias Edinger; Wolfgang Herr; Daniel Wolff
Source
Frontiers in Transplantation, Vol 3 (2024)
Subject
Language
English
ISSN
2813-2440
Abstract
IntroductionChronic graft-versus-host disease (cGvHD) is a serious late complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT).MethodsThis multicenter analysis determined the cumulative incidence (CI) of cGvHD and late acute GvHD (laGvHD) and its impact on transplantation-related mortality (TRM), relapse (R), and overall survival (OS) in 317 patients [296 adults, 21 pediatrics (