학술논문

A study of 3013 cases of hepatocellular carcinoma: Etiology and therapy before and during the current decade
Document Type
article
Source
JGH Open, Vol 5, Iss 9, Pp 1015-1018 (2021)
Subject
chronic hepatitis B
epidemiology
hepatocellular carcinoma
non‐alcoholic steatohepatitis
Diseases of the digestive system. Gastroenterology
RC799-869
Language
English
ISSN
2397-9070
Abstract
Abstract Background and Aim Hepatocellular carcinoma (HCC) is a significant global problem. With advances in HCC diagnosis and therapy, our hypothesis is that there are significant differences in the clinical characteristics and treatment of HCC over the years. Methods Patients with HCC between 1980 and 2018 from three major tertiary hospitals in Singapore were enrolled into a Research Electronic Data Capture database. Clinical characteristics and treatment of HCC were compared between those diagnosed before 2008 (cohort A) and during the current decade (ie from 2008 onwards) (cohort B). Results There were 3013 patients. Mean age of HCC diagnosis was significantly older in cohort B (68.6 vs 61.2 years, P