학술논문
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
Document Type
article
Author
Sarah Kim-Hellmuth; Matthias Bechheim; Benno Pütz; Pejman Mohammadi; Yohann Nédélec; Nicholas Giangreco; Jessica Becker; Vera Kaiser; Nadine Fricker; Esther Beier; Peter Boor; Stephane E. Castel; Markus M. Nöthen; Luis B. Barreiro; Joseph K. Pickrell; Bertram Müller-Myhsok; Tuuli Lappalainen; Johannes Schumacher; Veit Hornung
Source
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Insight into the genetic influence on the immune response is important for the understanding of interindividual variability in human pathologies. Here, the authors generate transcriptome data from human blood monocytes stimulated with various immune stimuli and provide a time-resolved response eQTL map.