학술논문
The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision
Document Type
article
Author
Paul W. Chrystal; Nils J. Lambacher; Lance P. Doucette; James Bellingham; Elena R. Schiff; Nicole C. L. Noel; Chunmei Li; Sofia Tsiropoulou; Geoffrey A. Casey; Yi Zhai; Nathan J. Nadolski; Mohammed H. Majumder; Julia Tagoe; Fabiana D’Esposito; Maria Francesca Cordeiro; Susan Downes; Jill Clayton-Smith; Jamie Ellingford; Genomics England Research Consortium; Omar A. Mahroo; Jennifer C. Hocking; Michael E. Cheetham; Andrew R. Webster; Gert Jansen; Oliver E. Blacque; W. Ted Allison; Ping Yee Billie Au; Ian M. MacDonald; Gavin Arno; Michel R. Leroux
Source
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Motile and non-motile cilia have distinct functions and protein complexes associated with them. Here, the authors show the conserved protein CFAP20 is important for both motile and non-motile cilia and is distinct from other ciliopathy-associated domains or macromolecular complexes.