학술논문
Patients with Alzheimer’s disease dementia show partially preserved parietal ‘hubs’ modeled from resting-state alpha electroencephalographic rhythms
Document Type
article
Author
Susanna Lopez; Claudio Del Percio; Roberta Lizio; Giuseppe Noce; Alessandro Padovani; Flavio Nobili; Dario Arnaldi; Francesco Famà; Davide V. Moretti; Annachiara Cagnin; Giacomo Koch; Alberto Benussi; Marco Onofrj; Barbara Borroni; Andrea Soricelli; Raffaele Ferri; Carla Buttinelli; Franco Giubilei; Bahar Güntekin; Görsev Yener; Fabrizio Stocchi; Laura Vacca; Laura Bonanni; Claudio Babiloni
Source
Frontiers in Aging Neuroscience, Vol 15 (2023)
Subject
Language
English
ISSN
1663-4365
Abstract
IntroductionGraph theory models a network by its nodes (the fundamental unit by which graphs are formed) and connections. ‘Degree’ hubs reflect node centrality (the connection rate), while ‘connector’ hubs are those linked to several clusters of nodes (mainly long-range connections).MethodsHere, we compared hubs modeled from measures of interdependencies of between-electrode resting-state eyes-closed electroencephalography (rsEEG) rhythms in normal elderly (Nold) and Alzheimer’s disease dementia (ADD) participants. At least 5 min of rsEEG was recorded and analyzed. As ADD is considered a ‘network disease’ and is typically associated with abnormal rsEEG delta (