학술논문
LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
De novo DNA methylation during mouse oogenesis occurs within transcribed regions. Here the authors investigate the role of species-specific long terminal repeats (LTRs)-initiated transcription units in regulating the oocyte methylome, identifying syntenic regions in mouse, rat and human with divergent DNA methylation associated with private LITs.