학술논문
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Document Type
article
Author
Tal Noy-Porat; Efi Makdasi; Ron Alcalay; Adva Mechaly; Yinon Levy; Adi Bercovich-Kinori; Ayelet Zauberman; Hadas Tamir; Yfat Yahalom-Ronen; Ma’ayan Israeli; Eyal Epstein; Hagit Achdout; Sharon Melamed; Theodor Chitlaru; Shay Weiss; Eldar Peretz; Osnat Rosen; Nir Paran; Shmuel Yitzhaki; Shmuel C. Shapira; Tomer Israely; Ohad Mazor; Ronit Rosenfeld
Source
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
Here, Noy-Porat, Makdasi et al. report the isolation of a panel of neutralizing mAbs selected against SARS-CoV-2 receptor-binding domain (RBD) from a phage display library constructed based on patient samples collected in the acute phase of the disease, which show efficient neutralizing activities against authentic virus in vitro.