학술논문
Pharmacological treatment of asthma in a cohort of adults during a 20-year period: results from the European Community Respiratory Health Survey I, II and III
Document Type
article
Author
Christer Janson; Simone Accordini; Lucia Cazzoletti; Isa Cerveri; Sebastien Chanoine; Angelo Corsico; Diogenes Seraphim Ferreira; Judith Garcia-Aymerich; David Gislason; Rune Nielsen; Ane Johannessen; Rain Jogi; Andrei Malinovschi; Jesús Martinez-Moratalla Rovira; Alessandro Marcon; Isabelle Pin; Jennifer Quint; Valerie Siroux; Enrique Almar; Valeria Bellisario; Karl A. Franklin; José A. Gullón; Mathias Holm; Joachim Heinrich; Dennis Nowak; José Luis Sánchez-Ramos; Joost J. Weyler; Deborah Jarvis; The members of the ECRHS I scientific team.; P. Burney; S. Chinn; C. Luczynska; D. Jarvis; E. Lai; P. Vermeire; H. Kesteloot; J. Bousquet; D. Nowak; J. Prichard; R. de Marco; B. Rijcken; J.M. Anto; J. Sunyer; J. Alves; G. Boman; N. Nielsen; P. Paoletti; M. Abramson; J. Kutin; F. van Bastelaer; R. Jõgi; A. Taytard; I. Pin; C. Pison; F. Neukirch; R. Liard; J. Knani; H-E. Wichmann; J. Heinrich; H. Magnussen; T. Gislason; D. Gislason; A. Marinoni; I. Cerveri; M. Bugiani; C. Bucca; C. Romano; L. Cascio; C. Campello; J. Droste; M. Kerkhof; A. Gulsvik; E. Omenaas; J. Martinez-Moratalla; E. Almar; A. Mateos; M. Arévalo; A. Sánchez; M. Vizcaya; X. Aguilar; A. Teixidó; J.M. Antó; M. Kogevinas; F. Burgos; J. Castellsagué; J. Roca; JB. Soriano; A. Tobías; N. Muiñozguren; J. Ramos González; A. Capelastegui; J. Maldonado Pérez; A. Pereira; J. Sánchez; J. Quiros; I. Huerta; F. Payo; N. Lindholm; P. Plaschke; C. Janson; E. Björnsson; L. Rosenhall; E. Norrman; B. Lundbäck; U. Ackermann-Liebrich; N. Küenzli; A. Perruchoud; M. Burr; J. Layzell; R. Hall; B. Harrison; The members of the ECRHS II scientific team.; J. Knox; M. Wjst; N. Kuenzli; E.H. Walters; J. Raven; J. Weyler; M. van Sprundel; V. Nelen; A. Soon; C. Raherison; J. Ferran-Quentin; B. Leynaert; M. Zureik; P.J. Bousquet; C. Frye; I. Meyer; E. Bjornsson; K.B. Jörundsdóttir; S. Villani; M. Ponzio; F. Frigerio; M. Comelli; M. Grassi; A. Corsico; R. Bono; P. Piccioni; E. Caria; A. Carosso; E. Migliore; G. Castiglioni; G. Verlato; E. Zanolin; S. Accordini; A. Poli; V. Lo Cascio; M. Ferrari; I. Cazzoletti; C. Svanes; B. Laerum; J. Martinez-Moratalla Rovira; C. Boix; G. González; J.M. Ignacio García; J. Solera; J. Damián; J.P. Zock; X. Basagaña; A. Jaen; C. Acosta; N. Muñozguren; J. Ramos; I. Urrutia; U. Aguirre; J. Maldonado; J.L. Sanchez; A. de la Vega; L. Palenciano; J. Azofra; A. Cañada; K. Toren; L. Lillienberg; A.C. Olin; B. Balder; A. Pfeifer-Nilsson; R. Sundberg; D. Norback; G. Wieslander; M. Gunnbjornsdottir; M. Soderberg; K.A. Franklin; B. Lundback; B. Forsberg; L. Nystrom; B. Dibbert; M. Hazenkamp; M. Brutsche; D. Seaton; The members of the ECRHS III scientific team.; M. Tumilty; J. Potts; T. Gislasson; T. Rochat; B. Leyneart; G. Benke; S. Dharmage; B. Thompson; S. Kaushik; M. Matheson; H. Bentouhami; H. Orru; P.O. Girodet; V. Siroux; J. Ferran; J.L. Cracowski; P. Demoly; A. Bourdin; I. Vachier; D. Soussan; D. Courbon; C. Neukirch; L. Alavoine; X. Duval; I. Poirier; E. Becker; G. Woelke; O. Manuwald; A-M. Kirsten; B. Benediktsdottir; E.S. Arnardottir; M. Clausen; G. Gudmundsson; L. Gudmundsdottir; H. Palsdottir; K. Olafsdottir; S. Sigmundsdottir; K. Bara-Jörundsdottir; A. Grosso; F. Albicini; E. Gini; E.M. Di Vincenzo; V. Ronzoni; F. Campanella; M. Gnesi; F. Manzoni; L. Rossi; O. Ferraro; R. Tassinari; V. Bellisario; G. Trucco; L. Calciano; L. Cazzoletti; A.M. Fratta Pasini; F. Locatelli; P. Marchetti; A. Marcon; E. Montoli; G. Nguyen; M. Olivieri; C. Papadopoulou; C. Posenato; G. Pesce; P. Vallerio; H.M. Boezen; A. Johannessen; T. Skorge; F. Gomez Real; S. García; A. Núñez; P. López; R. Sánchez; E. Mancebo; J-M. Antó; J. Garcia-Aymerich; A.E. Carsin; C. Sanjuas; S. Guerra; B. Jacquemin; P. Davdand Galdakao; S. Pascual; J. Antonio Maldonado; J.L. Sánchez; L. Palacios; N. Sánchez; M. Fernández; B. Robles; K. Torén; M. Holm; J-L. Kim; A-C. Olin; A. Dahlman-Höglund; L. Braback; L. Modig; B. Järvholm; K.A. Bertilsson; H. Franklin; C. Wahlgreen; B. Andersson; U. Spetz Nystrom; G.M. Bodinaa Lund; K. Nisser; N.M. Probst-Hensch; N. Künzli; D. Stolz; C. Schindler; J.M. Gaspoz; E. Zemp Stutz; M. Adam; C. Autenrieth; I. Curjuric; J. Dratva; A. Di Pasquale; R. Ducret-Stich; E. Fischer; L. Grize; A. Hensel; D. Keidel; A. Kumar; M. Imboden; N. Maire; A. Mehta; H. Phuleria; M. Ragettli; M. Ritter; E. Schaffner; G.A. Thun; A. Ineichen; T. Schikowski; M. Tarantino; M. Tsai; S. Kapur; R. Newson; N. Innes; A. Wilson
Source
ERJ Open Research, Vol 5, Iss 1 (2019)
Subject
Language
English
ISSN
2312-0541
23120541
23120541
Abstract
Asthma often remains uncontrolled, despite the fact that the pharmacological treatment has undergone large changes. We studied changes in the treatment of asthma over a 20-year period and identified factors associated with the regular use of inhaled corticosteroid (ICS) treatment. Changes in the use of medication were determined in 4617 randomly selected subjects, while changes in adults with persistent asthma were analysed in 369 participants. The study compares data from three surveys in 24 centres in 11 countries. The use of ICSs increased from 1.7% to 5.9% in the general population and the regular use of ICSs increased from 19% to 34% among persistent asthmatic subjects. The proportion of asthmatic subjects reporting asthma attacks in the last 12 months decreased, while the proportion that had seen a doctor in the last 12 months remained unchanged (42%). Subjects with asthma who had experienced attacks or had seen a doctor were more likely to use ICSs on a regular basis. Although ICS use has increased, only one-third of subjects with persistent asthma take ICSs on a regular basis. Less than half had seen a doctor during the last year. This indicates that underuse of ICSs and lack of regular healthcare contacts remains a problem in the management of asthma.