부산대학교 도서관

Rhea E Mathew,1 Molly Riehs,1 Anna V Blenda,2 Renee J Chosed,2 William S Wright2 1School of Medicine, University of South Carolina School of Medicine Greenville, Greenville, SC, USA; 2Department of Biomedical Sciences; University of South Carolina School of Medicine Greenville, Greenville, SC, USACorrespondence: William S Wright, University of South Carolina School of Medicine Greenville, Department of Biomedical Sciences, 701 Grove Road, Greenville, SC, 29605, USA, Tel +1 864 455 9865, Fax +1 864 455 8404, Email wrigh288@greenvillemed.sc.eduPurpose: Early identification of students at risk for poor United States Medical Licensing Examination® (USMLE) Step 1 examination (Step 1) performance allows medical schools to provide targeted intervention for those students. Therefore, determination of metrics that identify struggling students is necessary for proper intervention. We hypothesize that; 1) student performance on pre-matriculation metrics will correlate with their Molecular and Cellular Foundations of Medicine (FDNS) course performance and 2) student performance in the FDNS course and on specific FDNS course objectives will correlate with their Step 1 performance.Methods: This was a retrospective cohort study analyzing data for students matriculating to the University of South Carolina School of Medicine Greenville in 2018 and 2019. Linear regression analysis was conducted to assess the correlation between pre-matriculation metrics, performance in the FDNS course, performance on FDNS objectives, and USMLE Step 1 performance. Adjusted R-squared (adjusted r2) values were compared with a p-value at < 0.05.Results: The FDNS course grade correlated with pre-matriculation metrics of science undergraduate grade point average (uGPA), total uGPA, and the Medical College Admission Test (MCAT), adjusted r2 of 0.139, 0.121, 0.223, respectively. The FDNS course grade showed a stronger correlation to USMLE Step 1 performance (adjusted r2 = 0.257) than pre-matriculation metrics. USMLE Step 1 performance strongly correlated with FDNS course performance when two objectives, pertaining to anabolic and catabolic processes, regulation of cell cycle, and DNA replication and repair, were combined, adjusted r2 of 0.357.Conclusion: The FDNS course grade and performance on specific course objectives could serve as a predictor for USMLE Step 1 performance and provides a more targeted and concise approach to identification of low-performing students and subsequent intervention.Keywords: medical school curriculum, course objectives, course modifications, medical school performance, USMLE step 1