학술논문
Whole genome sequencing reveals hidden transmission of carbapenemase-producing Enterobacterales
Document Type
article
Author
Kalisvar Marimuthu; Indumathi Venkatachalam; Vanessa Koh; Stephan Harbarth; Eli Perencevich; Benjamin Pei Zhi Cherng; Raymond Kok Choon Fong; Surinder Kaur Pada; Say Tat Ooi; Nares Smitasin; Koh Cheng Thoon; Paul Anantharajah Tambyah; Li Yang Hsu; Tse Hsien Koh; Partha Pratim De; Thean Yen Tan; Douglas Chan; Rama Narayana Deepak; Nancy Wen Sim Tee; Andrea Kwa; Yiying Cai; Yik-Ying Teo; Natascha May Thevasagayam; Sai Rama Sridatta Prakki; Weizhen Xu; Wei Xin Khong; David Henderson; Nicole Stoesser; David W. Eyre; Derrick Crook; Michelle Ang; Raymond Tzer Pin Lin; Angela Chow; Alex R. Cook; Jeanette Teo; Oon Tek Ng; Carbapenemase-Producing Enterobacteriaceae in Singapore (CaPES) Study Group
Source
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Carbapenemase-producing Enterobacterales cause healthcare-associated infections but modes of transmission are not well understood. Here, the authors find evidence of transmission without direct patient contact, indicating presence of undetected environmental reservoirs, whilst half of the transmission events are likely due to plasmid-mediated transmission.