학술논문

Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats [Retraction]
Document Type
article
Source
Journal of Inflammation Research, Vol Volume 15, Pp 6069-6070 (2022)
Subject
re-purposing
in silico docking
jnk3 kinase
mcao stroke
jnk3 inhibitors
neuroinflammation
brain degeneration
Pathology
RB1-214
Therapeutics. Pharmacology
RM1-950
Language
English
ISSN
1178-7031
Abstract
Zulfiqar Z, Shah FA, Shafique S, et al. J Inflamm Res. 2020;13:1185–1205. The Editor and Publisher of Journal of Inflammation Research wish to retract the published article. Concerns were raised regarding the duplication of several images from Figures 9–11. Specifically, Figure 9E, HO-1, Striatum, Vehicle + Sham appears to have been duplicated with the same image for Figure 10B, p-JNK, Striatum, Vehicle + Sham. Figure 9E, HO-1, Striatum, Estazolam + MCAO appears to have been duplicated with the same image for Figure 11A, p-NFκB, Striatum, Vehicle + MCAO. Figure 9E, HO-1, Striatum, Vehicle + Sham appears to have been duplicated with the same image for Figure 11A, p-NFκB, Striatum, Vehicle + Sham. Figure 9E, HO-1, Striatum, Vehicle + Sham appears to have been duplicated with the same image for Figure 11B, TNF-α, Striatum, Vehicle + Sham. Figure 10B, p-JNK, Cortex, Vehicle + Sham appears to have been duplicated with the same image for Figure 11B, TNF-α, Cortex, Vehicle + Sham. Figure 10B, p-JNK, Cortex, Vehicle + MCAO appears to have been duplicated with the same image for Figure 11B, TNF-α, Cortex, Vehicle + MCAO. Figure 10B, p-JNK, Striatum, Leucovorin + MCAO appears to have been duplicated with the same image for Figure 11B, TNF-α, Striatum, Vehicle + MCAO. Figure 11A, p-NFκB, Striatum, Vehicle + Sham appears to have been duplicated with the same image for Figure 11B, TNF-α, Striatum, Vehicle + Sham. Figure 11A, p-NFκB, Cortex, Estazolam + MCAO appears to have been duplicated with the same image for Figure 11B, TNF-α, Cortex, Estazolam + MCAO. The authors responded to our queries but were unable to provide a satisfactory explanation for the duplicated images. The Editor requested for the article to be retracted and the authors were notified of this. Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.