학술논문

Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia
Document Type
article
Source
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Subject
Lymphopenia
COVID-19
Mortality
Hospital length of stay
Intensive care unit (ICU)
Medicine
Science
Language
English
ISSN
2045-2322
Abstract
Abstract Lymphopenia is a common feature of acute COVID-19 and is associated with increased disease severity and 30-day mortality. Here we aim to define the demographic and clinical characteristics that correlate with lymphopenia in COVID-19 and determine if lymphopenia is an independent predictor of poor clinical outcome. We analysed the ENTER-COVID (Epidemiology of hospitalized in-patient admissions following planned introduction of Epidemic SARS-CoV-2 to highly vaccinated COVID-19 naïve population) dataset of adults (N = 811) admitted for COVID-19 treatment in South Australia in a retrospective registry study, categorizing them as (a) lymphopenic (lymphocyte count