학술논문

The role of colloid 32p synoviorthesis in treatment of haemophilic arthropathy
Document Type
article
Source
Tehran University Medical Journal, Vol 68, Iss 6, Pp 364-371 (2010)
Subject
Haemophilia
synovectomy
synoviorthesis
Medicine (General)
R5-920
Language
Persian
ISSN
1683-1764
1735-7322
Abstract
"nBackground: Radioactive synoviorthesis by injection of safe radioisotopes into the joints affected to chronic arthritis is accounted as a novel method to treat haemophilic arthropathy. The main goal of this therapy would be decrease in frequency of hemarthrosis and consumption of coagulation factors. In this study we assessed the effect of radioactive synoviorthesis on the frequency of hemarthrosis, factor consumption and other related parameters. "n "nMethods: In an interventional study in Imam Khomeini Hospital in Tehran, Iran, after meeting of inclusion criteria and taking written consent, colloid 32p radiosynovectomy was performed for 56 joints with haemophilic arthropathy. After local anesthesia of injection site, one mci of 32P for large joints (knee) and 0.5 mci for small joints (ankle and elbow) was injected, respectively. Half of these doses were considered for children (age