학술논문
Association of chronic heart failure with mortality in old intensive care patients suffering from Covid‐19
Document Type
article
Author
Raphael Romano Bruno; Bernhard Wernly; Georg Wolff; Jesper Fjølner; Antonio Artigas; Bernardo Bollen Pinto; Joerg C. Schefold; Detlef Kindgen‐Milles; Philipp Heinrich Baldia; Malte Kelm; Michael Beil; Sigal Sviri; Peter Vernon vanHeerden; Wojciech Szczeklik; Arzu Topeli; Muhammed Elhadi; Michael Joannidis; Sandra Oeyen; Eumorfia Kondili; Brian Marsh; Finn H. Andersen; Rui Moreno; Susannah Leaver; Ariane Boumendil; Dylan W. De Lange; Bertrand Guidet; Hans Flaatten; Christian Jung; COVIP study group
Source
ESC Heart Failure, Vol 9, Iss 3, Pp 1756-1765 (2022)
Subject
Language
English
ISSN
2055-5822
24986836
24986836
Abstract
Abstract Aims Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID‐19). This prospective international multicentre study investigates the role of pre‐existing CHF on clinical outcomes of critically ill old (≥70 years) intensive care patients with COVID‐19. Methods and results Patients with pre‐existing CHF were subclassified as having ischaemic or non‐ischaemic cardiac disease; patients with a documented ejection fraction (EF) were subclassified according to heart failure EF: reduced (HFrEF, n = 132), mild (HFmrEF, n = 91), or preserved (HFpEF, n = 103). Associations of heart failure characteristics with the 30 day mortality were analysed in univariate and multivariate logistic regression analyses. Pre‐existing CHF was reported in 566 of 3917 patients (14%). Patients with CHF were older, frailer, and had significantly higher SOFA scores on admission. CHF patients showed significantly higher crude 30 day mortality [60% vs. 48%, P