학술논문
The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies
Document Type
article
Author
Hidefumi Suzuki; Ryota Abe; Miho Shimada; Tomonori Hirose; Hiroko Hirose; Keisuke Noguchi; Yoko Ike; Nanami Yasui; Kazuki Furugori; Yuki Yamaguchi; Atsushi Toyoda; Yutaka Suzuki; Tatsuro Yamamoto; Noriko Saitoh; Shigeo Sato; Chieri Tomomori-Sato; Ronald C. Conaway; Joan W. Conaway; Hidehisa Takahashi
Source
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Transcription termination is generally accompanied by the 3′-end processing of transcripts. Here the authors demonstrate a role for Mediator in transcript end site proximal pausing of replication-dependent histone genes.