학술논문

Dynamic transcriptome analysis reveals the gene network of gonadal development from the early history life stages in dwarf surfclam Mulinia lateralis
Document Type
article
Source
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-16 (2022)
Subject
Gonadal development
Sex differentiation
Gonad formation
Gametogenesis
Gene network
Mulinia lateralis
Medicine
Physiology
QP1-981
Language
English
ISSN
2042-6410
Abstract
Highlights Mulinia lateralis reaches sexual maturation within 2 months, facilitating comprehensive studies of gonadal development. A combined morphological and molecular analysis reveals the timing of gonad formation, sex differentiation and gametogenesis. WGCNA on 40 transcriptomes identifies key modules and molecular drivers of clam gonadal development. SOX2, FOXZ, HSFY, FOXL2 and HES1 are hub transcription factors for gonadal development of Mulinia lateralis.