학술논문
Quality of life in patients with epilepsy – single centre experience
Document Type
article
Author
Andreja Bujan Kovač; Željka Petelin Gadže; Katarina Ivana Tudor; Sibila Nanković; Vlatko Šulentić; Zdravka Poljaković; Goran Mrak; Monika Mudrovčić; Ira Brezak; Dragana Mijatović; Filip Đerke; Andrej Desnica; Jakob Nemir; Ivana Čajić; Petra Nimac Kozina; Biljana Đapić Ivančić; Borislav Radić; Sanja Hajnšek
Source
Acta Clinica Croatica, Vol 60., Iss Supplement 3, Pp 16-23 (2021)
Subject
Language
English
ISSN
0353-9466
1333-9451
1333-9451
Abstract
A prospective study was carried out at the Zagreb University Hospital Centre to evaluate the relationship between epilepsy, antiepileptic drugs (AEDs) and quality of life (QoL) in patients with epilepsy (PE), and its association with depressive symptoms and sexual dysfunction (SD). QoL was assessed by use of the Quality of Life in Epilepsy-31 Inventory (QOLIE-31), SD by the Arizona Sexual Experiences Scale (ASEX), and depressive symptoms by the Hamilton Rating Scale for Depression (HAM-D17). The study included 108 PE (women 63% and men 37% men), mean age 39.54±15.91 years. Focal type epilepsy was diagnosed in 14.8%, generalized type in 35.2%, and both types were present in 40.7% of study patients. Drug-resistant epilepsy (DRE) was present in 44/108 and vagus nerve stimulation (VNS) was implanted in 27/44 patients. The mean response on QOLIE-31 was 62.88±17.21 with no significant differences according to gender, type of epilepsy, and age. A statistically significantly lower QoL was found in the ‘Overall QoL’ domain (35-55 vs.