학술논문
Genetic and biological characterizations of a Newcastle disease virus from swine in china
Document Type
article
Author
Source
Virology Journal, Vol 9, Iss 1, p 129 (2012)
Subject
Language
English
ISSN
1743-422X
Abstract
Abstract Background Newcastle Disease Virus (NDV) has been considered to only infect avian species. However, one paramyxovirus named as Xiny10 was isolated from swine. The differences of Xiny10, another previous swine NDV (JL01) and vaccine strain La Sota were compared on the basis of sequences of the whole-lengthen Fusion (F) gene and biological characteristics. Findings Through serologic tests and sequence alignment, Xiny10 was proved as NDV. It has great differences with JL01 in virulence, biological characteristics, genotype and amino acid homology of F gene. The sequence alignment showed Xiny10 and La Sota both belonged to genotype II. It shared 97.3% to 98.7% identities with genotype II NDVs, which was higher than these strains from the other genotypes. Conclusions These above data suggested that the swine virus was NDV and it might be generated from La Sota.