학술논문

Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
Document Type
article
Source
Thoracic Cancer, Vol 12, Iss 18, Pp 2508-2512 (2021)
Subject
gene profiling
liquid biopsy
lung cancer
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Language
English
ISSN
1759-7714
1759-7706
Abstract
Abstract Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in which LB was useful in diagnosing ALK fusion‐positive lung cancer, selecting sequential ALK‐tyrosine kinase inhibitors, confirming uncommon EGFR mutations, and receiving biomarker‐compatible therapy.