학술논문
A novel score to estimate thrombus burden and predict intracranial hypertension in cerebral venous sinus thrombosis
Document Type
article
Author
Source
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-12 (2023)
Subject
Language
English
ISSN
1129-2377
Abstract
Abstract Background Current methods to evaluate the severity of cerebral venous sinus thrombosis (CVST) lack patient-specific indexes. Herein, a novel scoring method was investigated to estimate the thrombus burden and the intracranial pressure (ICP) of CVST. Methods In this retrospective study from January 2019 through December 2021, we consecutively enrolled patients with a first-time confirmed diagnosis of CVST by contrast-enhanced magnetic resonance venography (CE-MRV) or computed tomography venography (CTV). In these patients, a comprehensive CVST-Score was established using magnetic resonance black-blood thrombus imaging (MRBTI) to estimate the thrombus burden semi-quantitatively. The relationship between CVST-Score and ICP was explored to assess the potential of using the CVST-score to evaluate ICP noninvasively and dynamically. Results A total of 87 patients were included in the final analysis. The CVST-Scores in different ICP subgroups were as follows: 4.29±2.87 in ICP330mmH2O subgroup, respectively (p330mmH2O were 7.15 and 11.62, respectively (P