학술논문

Potential Protective Function of Adiponectin in Diabetic Retinopathy
Document Type
article
Source
Ophthalmology and Therapy, Vol 12, Iss 3, Pp 1519-1534 (2023)
Subject
Adiponectin
Diabetic retinopathy
Therapy targets
Ophthalmology
RE1-994
Language
English
ISSN
2193-8245
2193-6528
Abstract
Abstract Adiponectin, one of the most ubiquitous adipokines found in the blood, plays a major role in glucolipid metabolism and energy metabolism and regulation. In recent years, a growing body of research indicates that adiponectin also plays a significant role in diabetic retinopathy. In the present review, we specifically address the protective effects of adiponectin on the development and progression of diabetic retinopathy through improvement in insulin resistance, alleviation of oxidative stress, limiting of inflammation, and prevention of vascular remodeling, with the aim to explore new potential approaches and targets for the prevention and treatment of diabetic retinopathy.