학술논문

Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection
Document Type
article
Source
Emerging Infectious Diseases, Vol 29, Iss 2, Pp 381-388 (2023)
Subject
COVID-19
2019 novel coronavirus disease
coronavirus disease
severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
viruses
Medicine
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1080-6040
1080-6059
Abstract
Several studies have shown that neutralizing antibody levels correlate with immune protection from COVID-19 and have estimated the relationship between neutralizing antibodies and protection. However, results of these studies vary in terms of estimates of the level of neutralizing antibodies required for protection. By normalizing antibody titers, we found that study results converge on a consistent relationship between antibody levels and protection from COVID-19. This finding can be useful for planning future vaccine use, determining population immunity, and reducing the global effects of the COVID-19 pandemic