학술논문
RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells
Document Type
article
Author
Sébastien Durand; Marion Bruelle; Fleur Bourdelais; Bigitha Bennychen; Juliana Blin-Gonthier; Caroline Isaac; Aurélia Huyghe; Sylvie Martel; Antoine Seyve; Christophe Vanbelle; Annie Adrait; Yohann Couté; David Meyronet; Frédéric Catez; Jean-Jacques Diaz; Fabrice Lavial; Emiliano P. Ricci; François Ducray; Mathieu Gabut
Source
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Subject
Language
English
ISSN
2041-1723
Abstract
Pluripotency is coordinated at multiple levels of gene expression. Here the authors show that ribosome biogenesis is tightly regulated in embryonic stem cells (ESC) to control the translation of transcription and chromatin factors and dictate ESC fate.