학술논문
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Document Type
article
Author
Benedicte Sjo Tislevoll; Monica Hellesøy; Oda Helen Eck Fagerholt; Stein-Erik Gullaksen; Aashish Srivastava; Even Birkeland; Dimitrios Kleftogiannis; Pilar Ayuda-Durán; Laure Piechaczyk; Dagim Shiferaw Tadele; Jørn Skavland; Panagotis Baliakas; Randi Hovland; Vibeke Andresen; Ole Morten Seternes; Tor Henrik Anderson Tvedt; Nima Aghaeepour; Sonia Gavasso; Kimmo Porkka; Inge Jonassen; Yngvar Fløisand; Jorrit Enserink; Nello Blaser; Bjørn Tore Gjertsen
Source
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Subject
Language
English
ISSN
2041-1723
Abstract
The molecular mechanisms underlying response to chemotherapy in Acute myeloid leukemia (AML) remain to be explored. Here, the authors perform 36-dimensional mass cytometry in 32 AML patients during intensive chemotherapy and suggest functional signalling analysis for prognosis prediction early after treatment in AML.