학술논문

Associations between urinary bisphenol A and its analogues and semen quality: A cross-sectional study among Chinese men from an infertility clinic
Document Type
article
Source
Environment International, Vol 161, Iss , Pp 107132- (2022)
Subject
Bisphenols
Bisphenol A
Bisphenol F
Bisphenol S
Mixture exposure
Semen quality
Environmental sciences
GE1-350
Language
English
ISSN
0160-4120
Abstract
Human studies on association between bisphenol A (BPA) exposure and semen quality, mostly based on single urinary measurement, are inconsistent. There is limited human evidence on BPA analogues such as bisphenol F (BPF) and bisphenol S (BPS), and little is known on potential effects of bisphenol mixtures. We aimed to explore whether individual or mixtures of BPA, BPS and BPF assessed in repeated urinary measurements were associated with semen quality among 984 Chinese men from an infertility clinic. We found that higher BPA exposure was associated with increased odds ratios (ORs) of having below-reference sperm concentration, total sperm count, progressive motility and total motility (all P for trends