학술논문
Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
Document Type
article
Author
Source
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
The proliferation of pancreatic beta cells decreases with age, partly due to systemic changes. Here the authors identify Wisp1 as a circulating factor enriched in young serum that induces adult beta cell proliferation, supporting the idea that young blood factors may be useful to expand beta cell mass.