학술논문
Evaluation of cerebrovascular reactivity in moyamoya disease using oxygen-dependent magnetic resonance imaging
Document Type
article
Author
Source
iScience, Vol 27, Iss 2, Pp 108923- (2024)
Subject
Language
English
ISSN
2589-0042
Abstract
Summary: Moyamoya disease (MMD) is a rare cerebrovascular disorder marked by progressive stenosis of the internal carotid arteries. Assessing cerebral hemodynamics, specifically cerebrovascular reactivity (CVR), is vital for MMD management and prognosis. In this study, fMRI was performed in a prospective cohort of 47 patients with MMD and 32 healthy controls to investigate its utility in evaluating CVR and to explore the influence of cerebral posterior circulation compensation on CVR in MMD. The regions where the CVR values of participants with MMD were lower than those of healthy controls were primarily concentrated in the frontal, parietal, and temporal lobes (p