학술논문
Dietary protein intake affects the association between urinary iodine and clinically relevant depression: Evidence from NHANES 2007–2018
Document Type
article
Source
Food Science & Nutrition, Vol 11, Iss 8, Pp 4665-4677 (2023)
Subject
Language
English
ISSN
2048-7177
Abstract
Abstract Both iodine concentration and protein intake are important nutritional factors that may influence the development of depressive symptoms. However, there are no studies on the effect of protein intake on the relationship between iodine concentration and the risk of depression. The study aimed to explore the relationship between iodine and the risk of clinically relevant depression (CRD) according to protein intake. This study analyzed the adults (≥18 years) who participated in the 2007–2018 National Health and Nutrition Cross‐sectional Survey (N = 10,462). CRD was assessed using the Patient Health Questionnaire (PHQ‐9). Protein intake was assessed using two 24‐h dietary recalls and urinary iodine concentration (UIC) was measured using inductively coupled plasma dynamic response cell mass spectrometry. Weighted multivariate logistic regression and restrictive cubic splines were performed to assess the relationship between UIC and CRD according to protein category (low protein intake