학술논문

Artificial intelligence system, based on mjn-SERAS algorithm, for the early detection of seizures in patients with refractory focal epilepsy: A cross-sectional pilot study
Document Type
article
Source
Epilepsy & Behavior Reports, Vol 22, Iss , Pp 100600- (2023)
Subject
Seizure early detection
EEG analysis
Epilepsy
Epileptic seizures
Machine learning
Artificial intelligence
Neurology. Diseases of the nervous system
RC346-429
Neurophysiology and neuropsychology
QP351-495
Language
English
ISSN
2589-9864
Abstract
Around one-third of epilepsy patients develop drug-resistant seizures; early detection of seizures could help improve safety, reduce patient anxiety, increase independence, and enable acute treatment. In recent years, the use of artificial intelligence techniques and machine learning algorithms in different diseases, including epilepsy, has increased significantly. The main objective of this study is to determine whether the mjn-SERAS artificial intelligence algorithm developed by MJN Neuroserveis, can detect seizures early using patient-specific data to create a personalized mathematical model based on EEG training, defined as the programmed recognition of oncoming seizures before they are primarily initiated, usually within a period of a few minutes, in patients diagnosed of epilepsy. Retrospective, cross-sectional, observational, multicenter study to determine the sensitivity and specificity of the artificial intelligence algorithm. We searched the database of the Epilepsy Units of three Spanish medical centers and selected 50 patients evaluated between January 2017 and February 2021, diagnosed with refractory focal epilepsy who underwent video-EEG monitoring recordings between 3 and 5 days, a minimum of 3 seizures per patient, lasting more than 5 s and the interval between each seizure was greater than 1 h. Exclusion criteria included age