학술논문
Longitudinal changes of SARA scale in Friedreich ataxia: Strong influence of baseline score and age at onset
Document Type
article
Author
Luca Porcu; Mario Fichera; Lorenzo Nanetti; Eliana Rulli; Paola Giunti; Michael H. Parkinson; Alexandra Durr; Claire Ewenczyk; Sylvia Boesch; Wolfgang Nachbauer; Elisabetta Indelicato; Thomas Klopstock; Claudia Stendel; Francisco Javier Rodríguez de Rivera; Ludger Schöls; Zofia Fleszar; Ilaria Giordano; Claire Didszun; Anna Castaldo; Myriam Rai; Thomas Klockgether; Massimo Pandolfo; Jörg B. Schulz; Kathrin Reetz; Caterina Mariotti; for the EFACTS Study Group
Source
Annals of Clinical and Translational Neurology, Vol 10, Iss 11, Pp 2000-2012 (2023)
Subject
Language
English
ISSN
2328-9503
Abstract
Abstract Background The Scale for Assessment and Rating of Ataxia (SARA) is widely used in different types of ataxias and has been chosen as the primary outcome measure in the European natural history study for Friedreich ataxia (FA). Methods To assess distribution and longitudinal changes of SARA scores and its single items, we analyzed SARA scores of 502 patients with typical‐onset FA (